The emotions that we get by dating are changed as time goes by. Different chemicals, dopamine and oxytocin, have a significant impact on the human brain at the beginning of a relationship and in the mid-to-late stage of a relationship. Dopamine is a substance that is released when we feel pleasure, which leads us to repeat specific behavior that can give us pleasure. Oxytocin enhances intimacy and bond, and it is essential to maintain positive relationships. This article will look at how dopamine and oxytocin work in time of dating, and the importance of oxytocin that we must know to have a stable relationship. Not long after starting a relationship, dopamine plays an important role. Dopamine is a substance that causes pleasure in the human brain, it is released intensely when meeting a partner in the beginning of a relationship. We feel pleasure easily even from the small actions of a partner and are excited by trivial words. The excitement we experience at this time makes us feel good and pleasant, and dopamine is released from our brain. This dopamine controls our brain to maintain joyful feelings. Two people who are affected by dopamine continue to pursue the thrill they get from each other. However, there is a risk that we can become overly dependent on dopamine as it gives us temporary pleasure. The release of dopamine gradually decreases as we reach the middle stage of a relationship. The intense time of excitement is over, and pleasant and thrilling feelings change into stability. As the relationship progresses, we build trust and attachment to the partner. At this time, oxytocin is released. We develop relationships by understanding each other and sharing emotions. Oxytocin leads to enhance bond with each other to maintain a stable relationship with a partner. At this time, we gain emotional stability beyond the simple pleasure we feel in the beginning. The stable period of love led by oxytocin can be said to be the beginning of a true relationship in which to understand and embrace. We experience pleasure and excitement from dopamine in the beginning of a relationship, but they are just a temporary burst of emotions. The most important thing in a relationship is stability by oxytocin. If we focus too much on excitement, the relationship may be shallow and only short-term satisfaction. The relationship can develop continuously only when the trust and attachment of oxytocin are at work. To maintain a relationship for a long time, we must value not only the joy of dopamine but also the stability of oxytocin and strengthen the bond with each other.